This $952.9 Million Market You Haven't Heard Of? Hydrophobic Chromatography's Exploding

The global hydrophobic interaction chromatography market is projected to reach $952.9 million by 2033, growing at a CAGR of 7.5%.

PORTLAND, OR, UNITED STATES, June 26, 2025 /EINPresswire.com/ -- Allied Market Research published a report, titled, "Hydrophobic Interaction Chromatography Market by Product and Service (Product and Service), Sample Type (Monoclonal Antibodies, Vaccines, Cell Culture Sample, Plasma & Serum Sample, and Others), Application (Protein & Antibody Purification, Vaccine Development, Drug Discovery, and Food & Dietary Supplement Development), and End User (Pharmaceutical & Biopharmaceutical Companies, Contract Research Organizations & Contract Manufacturing Organizations, Research & Academic Institutes, and Others): Global Opportunity Analysis and Industry Forecast, 2024-2033". According to the report, the "hydrophobic interaction chromatography market" was valued at $461.9 million in 2023, and is estimated to reach $952.9 million by 2033, growing at a CAGR of 7.5% from 2024 to 2033.

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Prime determinants of growth

Increase in R&D expenditure in biopharmaceuticals, surge in demand for biologics & monoclonal antibodies (mAbs), and rise in adoption of biosimilars are the major factors that drive the growth of the hydrophobic interaction chromatography market. However, the lack of a skilled workforce and high initial investment & operating costs restrict market growth. Moreover, growth opportunities in emerging markets and technological advancements in hydrophobic interaction chromatography (HIC) are expected to open new avenues in the coming years.

The product segment held the largest market share in 2023.

By product and service, the product segment held the largest market share in 2023, accounting for more than four-fifths of the hydrophobic interaction chromatography market revenue and is estimated to maintain its leadership status throughout the forecast period. The same segment is expected to register the highest CAGR of 7.6% during the forecast period. This is attributed to growing demand for high-quality chromatography products, particularly in biopharmaceuticals and biotechnology industries. The increasing use of hydrophobic interaction chromatography for the purification of monoclonal antibodies, therapeutic proteins, and vaccines is driving the demand for advanced HIC resins and other chromatography products.

The monoclonal antibodies segment held the largest market share in 2023.

By sample type, the monoclonal antibodies segment held the largest market share in 2023, accounting for around two-fifths of the hydrophobic interaction chromatography market revenue and is estimated to maintain its leadership status throughout the forecast period. The same segment is expected to register the highest CAGR of 7.9% during the forecast period. This is attributed to the increase in demand for monoclonal antibodies in the treatment of cancer, autoimmune disorders, and other chronic diseases, which drives the need for efficient and reliable purification methods such as hydrophobic interaction chromatography (HIC).

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